From Mexico:
*Mexican Federal Highway 2 starts at the international dam at Lake Amistad near [wiki=e9b2554dabaf30ffb2184753e08233e6]Ciudad Acuña[/wiki], Coahuila and runs through [wiki=f4e0c48beece75430b58e6982d167452]Piedras Negras[/wiki], [wiki=ef3388cc5659bccb742fb8af762f1bfd]Colombia (Nuevo Leon)[/wiki], Nuevo Laredo [wiki=04489b9bcbf5d6df09ed1598dcc23f69]Reynosa[/wiki], and ends near [wiki=6c851b965778e56409a4963807c11122]Matamoros[/wiki], Tamaulipas.
*Mexican Federal Highway 85 starts in Nuevo Laredo and runs through [wiki=520b719ffeaafb7246f8e5da26d5c0a4]Monterrey[/wiki], Nuevo León, [wiki=4e732387a0d89bb2587f029d0b821795]Ciudad Victoria[/wiki], Tamaulipas, [wiki=ffd99f886d534659e7003660b9a209e3]Ciudad Valles[/wiki], San Luis Potosí, and [wiki=a8b279bd00a8a4d7a87e09b491dd1eac]Pachuca[/wiki], Hidalgo. It ends in [wiki=0b4596f8efe110dc55bbe564213dfb33]Mexico City[/wiki].
*Tamaulipas / Nuevo Leon Sate Highway 1 starts in Nuevo Laredo and runs through Anahuac and ends in Monterrey.
From the United States:
*Via International Bridges located in [wiki=95bd59e6ca6ec2c5ced24d56c35e0c85]Laredo[/wiki], Texas. Bridge 1 is the smaller bridge downtown, used largely for local traffic. Bridge 2 is the large bridge at the terminus of Interstate 35. Bridge 3 is the "International Commerce Bridge" and used only by trucks. An alternative to the Laredo bridges is to use the Colombia bridge, about 20km northwest of Laredo.
Quetzalcóatl International Airport (IPA: [ketsalˈkoː.aːtɬ]) (IATA: NLD, ICAO: MMNL) is an international airport located in Nuevo Laredo, Tamaulipas, Mexico. It is situated near the U.S.-Mexico border border that handles national and international air traffic for the city of Nuevo Laredo. Four daily direct flights to and from [wiki=0b4596f8efe110dc55bbe564213dfb33]Mexico City[/wiki] are available.
*Laredo International Airport[url=http://www.laredointernationalairport.com/]](IATA: LRD, ICAO: KLRD) is a public airport located 3 mi (4.8 km) northeast of Nuevo Laredo located in [[Laredo[/url]], Texas. The airport has scheduled direct flights to [wiki=09ea9b5e69df9e1385463fde29bc41cf]Dallas[/wiki]/[wiki=0390ec3843ee4ca87fe66257151a6d5a]Fort Worth[/wiki] (80 minutes) and [wiki=4483efb3ba720f9e8a3e32eb5acc0c0a]Houston[/wiki] (80 minutes) and [wiki=05c27bf00932572de28bf65a0539ba97]Las Vegas[/wiki] (165 minutes) via American Eagle, United Express, Allegiant.
Direct buses leave from, and depart for, Mexico City frequently with Grupo Senda. Bookings can be made online [http://portal.gruposenda.com/].